Article
Elevated low-density lipoprotein in Alzheimer's disease correlates with brain abeta 1-42 levels.
Biochemical and biophysical research communications - 27 Nov 1998
Kuo Y M, Emmerling M R, Bisgaier C L, Essenburg A D, Lampert H C, Drumm D, Roher A E
Abstract excerpt
Sera obtained in the immediate postmortem from 100 individuals, 64 neuropathologically diagnosed Alzheimer's disease (AD) cases and 36 nondemented controls, were analyzed for cholesterol, lipoproteins, apolipoproteins (Apo), and triglycerides. All individuals were ApoE genotyped, and the amounts...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Amyloid beta-Peptides
- Apolipoproteins
- Apolipoproteins E
- Brain
- Cardiovascular Diseases
- Genotype
- Humans
- Lipids
- Lipoproteins
- Lipoproteins, LDL
- Peptide Fragments
- Risk Factors