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Article

Novel OXA-10-Derived Extended-Spectrum β-Lactamases Selected In Vivo or In Vitro

1 Dec 1998

Abstract excerpt

A clinical isolate of Pseudomonas aeruginosa, PAe191, was found to be highly resistant to all anti-Pseudomonas beta-lactam antibiotics (except imipenem) and resistant also to aminoglycosides. It produced a beta-lactamase (with an apparent pI of 7.6) which was not inhibited by clavulanic acid. Cloning and characterization of the beta-lactamase gene showed that it coded for a novel extended-spectrum OXA-10 variant,...

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Share to Antibiotic Resistance in Bacteria
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PMID: 9835500
DOI: 10.1128/aac.42.12.3113

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