Article
Carbapenems as inhibitors of OXA-13, a novel, integron-encoded beta-lactamase in Pseudomonas aeruginosa.
Microbiology (Reading, England) - 1 Apr 1998
Mugnier P, Podglajen I, Goldstein F W, Collatz E
Abstract excerpt
A clinical Pseudomonas aeruginosa strain, PAe391, was found to be resistant to a number of antibiotics including ticarcillin, piperacillin, cefsulodin and amikacin, and a disk diffusion assay showed evidence of pronounced synergy between imipenem and various beta-lactam antibiotics. Cloning and n...
Topics
- Anti-Bacterial Agents
- Bacterial Outer Membrane Proteins
- Base Sequence
- Carbapenems
- Cephalosporinase
- Drug Resistance, Microbial
- Genes, Bacterial
- Humans
- Immunoblotting
- Molecular Sequence Data
- Phenotype
- Pseudomonas aeruginosa
- beta-Lactamase Inhibitors
- beta-Lactamases