Article
Binding specificity of a class II-restricted hepatitis B epitope by DR molecules from responder and nonresponder vaccine recipients.
Human immunology - 1 Dec 1998
Schuenke K W, Cook R G, Rich R R
Abstract excerpt
A small but significant proportion of people who receive the hepatitis B vaccine do not produce anti-hepatitis B antibodies, a phenomenon associated with certain human leukocyte antigen (HLA) class II haplotypes. We were interested in determining whether natural allelic differences between two HL...
Topics
- Alleles
- Biosensing Techniques
- Cloning, Molecular
- Enzyme-Linked Immunosorbent Assay
- HLA-DR Antigens
- HLA-DR4 Antigen
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Surface Antigens
- Hepatitis B Vaccines
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Immunodominant Epitopes
- Kinetics
- Peptides
- Receptors, Antigen, T-Cell
- T-Lymphocytes