Article
PRS5, the fifth member of the phosphoribosyl pyrophosphate synthetase gene family in Saccharomyces cerevisiae, is essential for cell viability in the absence of either PRS1 or PRS3.
Journal of bacteriology - 1 Dec 1998
Hernando Y, Parr A, Schweizer M
Abstract excerpt
In Saccharomyces cerevisiae, an open reading frame, YOL061w, encodes a polypeptide with sequence similarity to the four known 5-phosphoribosyl-1(alpha)-pyrophosphate synthetase (PRS) genes since it contains a divalent cation binding site and a phosphoribosyl pyrophosphate binding site. We regard...
Topics
- Base Sequence
- Binding Sites
- DNA Primers
- DNA, Fungal
- Gene Deletion
- Genes, Fungal
- Multigene Family
- Mutagenesis, Insertional
- Open Reading Frames
- Phenotype
- Ribose-Phosphate Pyrophosphokinase
- Saccharomyces cerevisiae