Article
PEDF (pigment epithelium-derived factor) promotes increase and maturation of pigment granules in pigment epithelial cells in neonatal albino rat retinal cultures.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Aug 1998
Malchiodi-Albedi F, Feher J, Caiazza S, Formisano G, Perilli R, Falchi M, Petrucci T C, Scorcia G, Tombran-Tink J
Abstract excerpt
Pigment Epithelium-Derived Factor (PEDF), purified from human retinal pigment epithelial (RPE) cell culture medium, is a neurotrophic factor which potentiates the differentiation of human Y-79 retinoblastoma cells and increases the survival of cerebellar granule cells. To investigate the effects...
Topics
- Animals
- Animals, Newborn
- Autocrine Communication
- Cell Adhesion
- Cell Differentiation
- Cells, Cultured
- Cellular Senescence
- Cytoplasmic Granules
- Eye Proteins
- Humans
- Nerve Growth Factors
- Phenotype
- Pigment Epithelium of Eye