In vitro phenotypic modification of pigmented epithelium cells from human eye at early stages of development.

doi:10.1007/s10517-009-0657-1

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Article

In vitro phenotypic modification of pigmented epithelium cells from human eye at early stages of development.

Bulletin of experimental biology and medicine - 1 Jul 2009

Milyushina L A, Poltavtseva R A, Marei M V, Podgornyi O V, Sukhikh G T, Aleksandrova M A

Abstract excerpt

Multipotent characteristics of human fetal (9-11.5 weeks) pigmented epithelial retinal cells and capacity to transdifferentiation in neuronal direction were studied in vitro under different culturing conditions. The cultures were analyzed using a wide spectrum of antibodies. It was found that pigmented epithelium of human eye is a heterogeneous cell population with three subtypes differing by adhesion...

Topics

Cell Adhesion
Cell Differentiation
Cell Movement
Humans
Immunohistochemistry
Phenotype
Retinal Pigment Epithelium

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Open in PubMed

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PMID: 19902111
DOI: 10.1007/s10517-009-0657-1

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