Evidence that a gene for essential tremor maps to chromosome 2p in four families.

doi:10.1002/mds.870130621

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Article

Evidence that a gene for essential tremor maps to chromosome 2p in four families.

Movement disorders : official journal of the Movement Disorder Society - 1 Nov 1998

Higgins J J, Loveless J M, Jankovic J, Patel P I

Abstract excerpt

In this Journal, we previously reported genetic linkage between loci on chromosome (chr)2p(ETM) and dominantly inherited essential tremor (ET) in a large American kindred of Czech ancestry. Other investigators reported another ET susceptibility locus on chr 3q (FET1) which accounted for over half...

Topics

Adult
Age of Onset
Chromosome Aberrations
Chromosome Disorders
Chromosomes, Human, Pair 2
Female
Genes, Dominant
Genetic Linkage
Genetic Markers
Genotype
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lod Score

Male

Middle Aged

Pedigree

Tremor

United States

Source

Open in PubMed

Identifiers

PMID: 9827627
DOI: 10.1002/mds.870130621

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9827627-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Evidence that a gene for essential tremor maps to chromosome 2p in four families.PMID 9827627Read ↗

A gene (ETM) for essential tremor maps to chromosome 2p22-p25.Semantic proximity Read ↗

Genomewide scans in North American families reveal genetic linkage of essential tremor to a region on chromosome 6p23.Semantic proximity Read ↗

Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology.Semantic proximity Read ↗

Integrated physical map of the human essential tremor gene region (ETM2) on chromosome 2p24.3-p24.2.Semantic proximity Read ↗

No association with the ETM2 locus in Czech patients with familial essential tremor.Semantic proximity Read ↗

Mapping of a familial essential tremor gene, FET1, to chromosome 3q13.Semantic proximity Read ↗

An Exploratory Analysis of Essential Tremor and Associated PhenotypesSemantic proximity Read ↗

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis.Semantic proximity Read ↗

Update on genetics of essential tremor.Semantic proximity Read ↗

Autosomal dominant essential tremor: a novel family with anticipation.Semantic proximity Read ↗

Whole Genome Sequencing and Rare Variant Analysis in Essential Tremor FamiliesSemantic proximity Read ↗

An Exploratory Analysis of Essential Tremor and Associated Phenotypes.Semantic proximity Read ↗

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