Article
Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome.
Proceedings of the Association of American Physicians - 1 Jan 2000
Peek R M, Thompson S A, Donahue J P, Tham K T, Atherton J C, Blaser M J, Miller G G
Abstract excerpt
Most persons infected with Helicobacter pylori strains that produce vacuolating cytotoxin and possess cytotoxin-associated gene A (cagA) genotype nonetheless remain asymptomatic, suggesting that additional genes are important in virulence. We hypothesized that adherence to gastric epithelium prov...
Topics
- Amino Acid Sequence
- Bacterial Outer Membrane Proteins
- Base Sequence
- Cell Adhesion
- Conserved Sequence
- Epithelial Cells
- Gastric Mucosa
- Gene Expression
- Genes, Bacterial
- Genetic Variation
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Immunity, Mucosal