Article
Evaluation of the clinical relevance of the iceA1 gene in patients with Helicobacter pylori infection in Japan.
Scandinavian journal of gastroenterology - 1 Jan 2000
Nishiya D, Shimoyama T, Fukuda S, Yoshimura T, Tanaka M, Munakata A
Abstract excerpt
BACKGROUND: A novel Helicobacter pylori gene, iceA, has two allelic variants, and the iceA1 strain is associated with peptic ulcer disease. The aims of this study were to evaluate whether the possession of iceA1 gene is associated with gastric cancer or the severity of gastritis. METHODS: Ninety-seven subjects (46 patients with early gastric cancer and 51 control subjects) infected with H. pylori were studied....
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