Article
Molecular and genetic characterization of a Taf1p domain essential for yeast TFIID assembly.
Molecular and cellular biology - 1 Jun 2004
Singh Madhu V, Bland Christin E, Weil P Anthony
Abstract excerpt
Yeast Taf1p is an integral component of the multiprotein transcription factor TFIID. By using coimmunoprecipitation assays, coupled with a comprehensive set of deletion mutants encompassing the entire open reading frame of TAF1, we have discovered an essential role of a small portion of yeast Taf1p. This domain of Taf1p, termed region 4, consisting of amino acids 200 to 303, contributes critically to the assembly...
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