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Article

Diversity of naturally occurring Epstein-Barr virus revealed by nucleotide sequence polymorphism in hypervariable domains in the BamHI K and N subgenomic regions.

The Journal of general virology - 1 Nov 1998

Triantos D, Boulter A W, Leao J C, Di Alberti L, Porter S R, Scully C M, Birnbaum W, Johnson N W, Teo C G

Abstract excerpt

The extent of nucleotide sequence microheterogeneity varies among subgenomic regions of Epstein-Barr virus (EBV). We examined, in EBV-carrying lymphoid cell lines, the extent of polymorphism in EBV DNA fragments amplified from the BamHI E, K, N and Z regions, and then investigated the diversity of the more hypervariable regions in tissues and body fluids. In cell lines, sequence dissimilarities in a...

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PMID: 9820158
DOI: 10.1099/0022-1317-79-11-2809

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