Article
The influence of human genetic variation on Epstein-Barr virus sequence diversity.
Scientific reports - 25 Feb 2021
Rüeger Sina, Hammer Christian, Loetscher Alexis, McLaren Paul J, Lawless Dylan, Naret Olivier, Khanna Nina, Bernasconi Enos, Cavassini Matthias, Günthard Huldrych F, Kahlert Christian R, Rauch Andri, Depledge Daniel P, Morfopoulou Sofia, Breuer Judith, Zdobnov Evgeny, Fellay Jacques
Abstract excerpt
Epstein-Barr virus (EBV) is one of the most common viruses latently infecting humans. Little is known about the impact of human genetic variation on the large inter-individual differences observed in response to EBV infection. To search for a potential imprint of host genomic variation on the EBV sequence, we jointly analyzed paired viral and human genomic data from 268 HIV-coinfected individuals with CD4 + T...
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