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Article

Early Epstein-Barr Virus Genomic Diversity and Convergence toward the B95.8 Genome in Primary Infection.

Journal of virology - 15 Jan 2018

Weiss Eric R, Lamers Susanna L, Henderson Jennifer L, Melnikov Alexandre, Somasundaran Mohan, Garber Manuel, Selin Liisa, Nusbaum Chad, Luzuriaga Katherine

Abstract excerpt

Over 90% of the world's population is persistently infected with Epstein-Barr virus. While EBV does not cause disease in most individuals, it is the common cause of acute infectious mononucleosis (AIM) and has been associated with several cancers and autoimmune diseases, highlighting a need for a preventive vaccine. At present, very few primary, circulating EBV genomes have been sequenced directly from infected...

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Identifiers

PMID: 29093087
DOI: 10.1128/JVI.01466-17
PMCID: PMC5752928

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