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Article

Interleukin-10 promoter polymorphism is associated with the predisposition to the development of IgA nephropathy and focal segmental glomerulosclerosis in Korea.

Journal of Korean medical science - 1 Dec 2005

Chin Ho Jun, Na Ki Young, Kim Soo Jin, Oh Kook-Hwan, Kim Yon Su, Lim Chun Soo, Kim Suhnggwon, Chae Dong-Wan

Abstract excerpt

The roles of interleukin-10 (IL-10) have been emphasized in several models of glomerulonephritis (GN). Three biallelic polymorphisms within the IL-10 promoter region, at positions -1,082, -819, and -592 from the transcription initiation site, were shown to affect the level of IL-10 production. To investigate the effect of IL-10 promoter polymorphisms on the predisposition to development of GN in Korea, IL-10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerulosclerosis, Focal Segmental

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Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

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Identifiers

PMID: 16361810
DOI: 10.3346/jkms.2005.20.6.989
PMCID: PMC2779332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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