Article
Association between bleomycin hydrolase and Alzheimer's disease in caucasians.
Annals of neurology - 1 Nov 1998
Farrer L A, Abraham C R, Haines J L, Rogaeva E A, Song Y, McGraw W T, Brindle N, Premkumar S, Scott W K, Yamaoka L H, Saunders A M, Roses A D, Auerbach S A, Sorbi S, Duara R, Pericak-Vance M A, St George-Hyslop P H
Abstract excerpt
A recent study showed modest evidence for an increased frequency of the bleomycin hydrolase (BH) V/V genotype in Alzheimer's disease (AD) patients compared with non-demented controls. To test this hypothesis, we examined this polymorphism in 621 rigorously evaluated patients and 502 control subjects (all caucasian) but were unable to detect an association between BH and AD even after controlling for age, gender,...
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