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Article

Comprehensive genotypic analysis of human prostate cancer cell lines and sublines derived from metastases after orthotopic implantation in nude mice.

International journal of oncology - 1 Oct 2002

Lensch Ramona, Götz Claudia, Andres Christine, Bex Axel, Lehmann Jan, Zwergel Thomas, Unteregger Gerhard, Kamradt Jörn, Stoeckle Michael, Wullich Bernd

Abstract excerpt

We recently reported on a prostate cancer progression model which was based on repeated orthotopic implantation of human prostate cancer cell lines into athymic nude mice leading to an increase of tumor cell aggressiveness. To assess progression-associated clonal evolution of genotypic changes, we now performed comparative cytogenetic characterization of the original cell lines DU145 and PC3 with derived sublines...

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PMID: 12239607

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MYC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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