Article
The expression of the CD44 variant exon 6 is associated with lymph node metastasis in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 1997
Miyoshi T, Kondo K, Hino N, Uyama T, Monden Y
Abstract excerpt
Recently, it was suggested that splice variants of the surface glycoprotein CD44 (CD44v) were associated with tumor metastasis in some cancers. We examined the expression of variant forms of CD44 in 31 non-small cell lung carcinomas (NSCLCs) and in 8 normal lung tissue samples by reverse transcri...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antigens, CD
- Carcinoma, Non-Small-Cell Lung
- DNA Primers
- Exons
- Female
- Genetic Variation
- Humans
- Hyaluronan Receptors
- Lung
- Lung Neoplasms
- Lymphatic Metastasis
- Male
- Middle Aged
- Neoplasm Staging
- Reverse Transcriptase Polymerase Chain Reaction