Article
Differential expression of CD44 splice variants in malignant and benign pleural effusions.
The Tohoku journal of experimental medicine - 1 Aug 1996
Tojo N, Inase N, Ichioka M, Miyazato I, Nara N
Abstract excerpt
Expression of CD44 isoform that contains variant exons (v1-v10) has been implicated in tumor progression and metastasis. Especially, CD44 isoform containing v6 (CD44v6) and that containing v7 (CD44v7) were shown to confer full metastatic behavior on tumor cells. We examined the expression of CD44v6 and CD44v7 in malignant pleural effusions (13 lung cancers and 4 non-lung cancers) and in benign pleural effusions...
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