Article
RuvAB acts at arrested replication forks.
Cell - 30 Oct 1998
Seigneur M, Bidnenko V, Ehrlich S D, Michel B
Abstract excerpt
Replication arrest leads to the occurrence of DNA double-stranded breaks (DSB). We studied the mechanism of DSB formation by direct measure of the amount of in vivo linear DNA in Escherichia coli cells that lack the RecBCD recombination complex and by genetic means. The RuvABC proteins, which cat...
Topics
- Bacterial Proteins
- DNA Helicases
- DNA Replication
- DNA, Bacterial
- DNA-Binding Proteins
- DnaB Helicases
- Electrophoresis, Gel, Pulsed-Field
- Endodeoxyribonucleases
- Escherichia coli
- Escherichia coli Proteins
- Exodeoxyribonuclease V
- Exodeoxyribonucleases
- Models, Biological
- Multienzyme Complexes
- Mutation
- Phenotype
- Rec A Recombinases
- Recombination, Genetic
