Efficiency of cell culture derivation from blastula embryos and of chimera formation in the medaka (Oryzias latipes) depends on donor genotype and passage number.

doi:10.1007/s004270050220

Back to search

Article

Efficiency of cell culture derivation from blastula embryos and of chimera formation in the medaka (Oryzias latipes) depends on donor genotype and passage number.

Development genes and evolution - 1 Dec 1998

Hong Y, Winkler C, Schartl M

Abstract excerpt

Embryonic stem (ES) cells from early vertebrate embryos only rarely retain their full developmental potential under in vitro culture conditions, but undergo differentiation and lose their ability for chimeric embryogenesis. This is reflected by the fact that the ES cell technology to date could o...

Topics

Animals
Blastocyst
Cell Transplantation
Cells, Cultured
Chimera
Female
Genotype
Male
Mice
Oryzias
Pigmentation
Stem Cells

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.