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Article

Host cell-virus cross talk: phosphorylation of a hepatitis B virus envelope protein mediates intracellular signaling.

Journal of virology - 1 Dec 1998

Rothmann K, Schnölzer M, Radziwill G, Hildt E, Moelling K, Schaller H

Abstract excerpt

Phosphorylation of cytosolic pre-S domains of the duck hepatitis B virus (DHBV) large envelope protein (L) was identified as a regulatory modification involved in intracellular signaling. By using biochemical and mass spectrometric analyses of phosphopeptides obtained from metabolically radiolabeled L protein, a single phosphorylation site was identified at serine 118 as part of a PX(S/T)P motif, which is...

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Identifiers

PMID: 9811754
DOI: 10.1128/JVI.72.12.10138-10147.1998
PMCID: PMC110552

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