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Article

Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection.

Journal of virology - 1 Dec 1998

Monaco M C, Jensen P N, Hou J, Durham L C, Major E O

Abstract excerpt

Progressive multifocal leukoencephalopathy is a demyelinating disease of the human central nervous system that results from lytic infection of oligodendrocytes by the polyomavirus JC (JCV). Originally, JCV was thought to replicate exclusively in human glial cells, specifically oligodendrocytes. However, we have recently shown that JCV can replicate in cells of lymphoid origin such as hematopoietic precursor...

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Identifiers

PMID: 9811728
DOI: 10.1128/JVI.72.12.9918-9923.1998
PMCID: PMC110504

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Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection.PMID 9811728Read ↗

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Detection of the archetypal regulatory region of JC virus from the tonsil tissue of patients with tonsillitis and tonsilar hypertrophySemantic proximity Read ↗

Traffic of JC Virus from Sites of Initial Infection to the Brain: The Path to Progressive Multifocal LeukoencephalopathySemantic proximity Read ↗

Detection of JC Virus DNA and Proteins in the Bone Marrow of HIV‐Positive and HIV‐Negative Patients: Implications for Viral Latency and Neurotropic TransformationSemantic proximity Read ↗

Polyomavirus JC in the context of immunosuppression: a series of adaptive, DNA replication-driven recombination events in the development of progressive multifocal leukoencephalopathy.Semantic proximity Read ↗

Molecular characterization of JC virus in progressive multifocal leukoencephalopathy cases from India.Semantic proximity Read ↗

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Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathySemantic proximity Read ↗

Presence and expression of JCV early gene large T Antigen in the brains of immunocompromised and immunocompetent individualsSemantic proximity Read ↗

JC virus regulatory region rearrangements and genotypes in progressive multifocal leukoencephalopathy: two independent aspects of virus variation.Semantic proximity Read ↗

Isolation of a possible archetypal JC virus DNA sequence from nonimmunocompromised individualsSemantic proximity Read ↗

JC Virus Regulatory Region Tandem Repeats in Plasma and Central Nervous System Isolates Correlate with Poor Clinical Outcome in Patients with Progressive Multifocal LeukoencephalopathySemantic proximity Read ↗

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