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Article

Hepatitis A virus sequence detected in clotting factor concentrates associated with disease transmission.

Biologicals : journal of the International Association of Biological Standardization - 1 Jun 1998

Robertson B H, Alter M J, Bell B P, Evatt B, McCaustland K A, Shapiro C N, Sinha S D, Souci J M

Abstract excerpt

Since the early 1990s hepatitis A virus (HAV) infections among recipients of solvent-detergent treated factor VIII concentrates have occurred in Europe, South Africa and the United States. A review of the epidemiological and laboratory-based investigations of the outbreaks in Germany and Ireland were consistent with transmission by factor concentrates but limited information about transmission based upon nucleic...

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PMID: 9811512
DOI: 10.1006/biol.1998.0139

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