Article
Contamination of coagulation factor concentrates with human parvovirus B19 genotype 1 and 2.
Thrombosis and haemostasis - 1 Oct 2004
Schneider Beate, Becker Maria, Brackmann Hans-Hermann, Eis-Hübinger Anna Maria
Abstract excerpt
Human parvovirus B19 (B19) DNA has frequently been detected in plasma-derived coagulation factor concentrates. Furthermore, transmission of B19 infection was observed, indicating presence of the infectious virus despite routine viral inactivation/removal procedures during the manufacturing process. Recently, human parvovirus DNA isolates, variant from B19, have been identified resulting in classification of B19...
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