Article
A new cluster of hepatitis A infection in hemophiliacs traced to a contaminated plasma pool.
Journal of medical virology - 1 Feb 1999
Chudy M, Budek I, Keller-Stanislawski B, McCaustland K A, Neidhold S, Robertson B H, Nübling C M, Seitz R, Löwer J
Abstract excerpt
Recently, several clusters of hepatitis A have been observed among hemophiliacs linked to factor VIII concentrates treated for virus inactivation solely with the solvent/detergent (S/D) method, a procedure that does not affect nonenveloped viruses such as the hepatitis A virus (HAV). A new outbre...
Topics
- Adult
- Blood-Borne Pathogens
- Cluster Analysis
- Disease Outbreaks
- Factor VIII
- Genotype
- Germany
- Hemophilia A
- Hepatitis A
- Hepatovirus
- Humans
- Middle Aged
- Phylogeny
- RNA, Viral
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Analysis, DNA
- Sequence Homology, Nucleic Acid
- Viral Proteins
