Article
Is a low leptin concentration, a low resting metabolic rate, or both the expression of the "thrifty genotype"? Results from Mexican Pima Indians.
The American journal of clinical nutrition - 1 Nov 1998
Fox C S, Esparza J, Nicolson M, Bennett P H, Schulz L O, Valencia M E, Ravussin E
Abstract excerpt
BACKGROUND: The high prevalence of obesity and type 2 diabetes in some populations is believed to be the expression of a "thrifty genotype," which conferred survival advantages during periods of harsh environmental conditions, but has become a liability in industrialized environments of abundance...
Topics
- Adult
- Basal Metabolism
- Blood Glucose
- Calorimetry, Indirect
- Diabetes Mellitus, Type 2
- Female
- Genotype
- Humans
- Indians, North American
- Insulin
- Leptin
- Life Style
- Linear Models
- Male
- Mexico
- Middle Aged
- Obesity
- Proteins