The products of ribbon and raw are necessary for proper cell shape and cellular localization of nonmuscle myosin in Drosophila.

doi:10.1006/dbio.1998.9036

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Article

The products of ribbon and raw are necessary for proper cell shape and cellular localization of nonmuscle myosin in Drosophila.

Developmental biology - 1 Nov 1998

Blake K J, Myette G, Jack J

Abstract excerpt

Mutations in the genes rib and raw cause defects in the morphology of a number of tissues in homozygous mutant embryos. A variety of tubular epithelial tissues adopt a wide, round shape in mutants and dorsal closure fails. Cells of the normal tubular epithelia are columnar and wedge-shaped, and cells of the epidermis become elongated dorsoventrally as dorsal closure occurs. However, the cells of mutants are round...

Topics

Actins
Animals
Cell Size
Cytoskeletal Proteins
Cytoskeleton
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Immunohistochemistry
Malpighian Tubules
Membrane Proteins
Muscle Contraction
Mutation
Myosin Heavy Chains
Myosins
Phenotype
Salivary Glands

Source

Open in PubMed

Identifiers

PMID: 9806782
DOI: 10.1006/dbio.1998.9036

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