Article
Isolation of cDNA clones coding for IgE autoantigens with serum IgE from atopic dermatitis patients
1 Nov 1998
Abstract excerpt
Recently we demonstrated that a high percentage of atopic dermatitis (AD) patients displayed specific immunoglobulin E reactivity to human proteins. Here we show that IgE autoreactivity is found predominantly in AD patients with severe skin manifestations and reveal the molecular nature of four IgE autoantigens. An expression cDNA library constructed from a human epithelial cell line (A 431) was screened with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
