A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10.

doi:10.1038/3123

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Article

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10.

Nature genetics - 1 Nov 1998

Hager J, Dina C, Francke S, Dubois S, Houari M, Vatin V, Vaillant E, Lorentz N, Basdevant A, Clement K, Guy-Grand B, Froguel P

Abstract excerpt

Obesity, a common multifactorial disorder, is a major risk factor for type 2 diabetes, hypertension and coronary heart disease (CHD). According to the definition of the World Health Organization (WHO), approximately 6-10% of the population in Westernized countries are considered obese. Epidemiolo...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 10
Female
Gene Frequency
Genetic Linkage
Genetic Markers
Genome, Human
Genotype
Humans
Leptin
Male
Obesity
Phenotype
Proteins
Quantitative Trait, Heritable

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Open in PubMed

Identifiers

PMID: 9806554
DOI: 10.1038/3123

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POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9806554-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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