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Chromosome 2 Sequence of the Human Malaria ParasitePlasmodium falciparum

6 Nov 1998

Abstract excerpt

Chromosome 2 of Plasmodium falciparum was sequenced; this sequence contains 947,103 base pairs and encodes 210 predicted genes. In comparison with the Saccharomyces cerevisiae genome, chromosome 2 has a lower gene density, introns are more frequent, and proteins are markedly enriched in nonglobular domains. A family of surface proteins, rifins, that may play a role in antigenic variation was identified. The...

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PMID: 9804551
DOI: 10.1126/science.282.5391.1126

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