Article
Genetic and physical delineation of the region of the mouse deafness mutation shaker-2.
Biochemical and biophysical research communications - 8 May 1997
Wakabayashi Y, Kikkawa Y, Matsumoto Y, Shinbo T, Kosugi S, Chou D, Furuya M, Jishage K, Noda T, Yonekawa H, Kominami R
Abstract excerpt
A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a contig consisting of 21 BAC clones across an approximately 700-kb region of sh-2. This covers the...
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