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Article

hoxX (hypX) is a functional member of the Alcaligenes eutrophus hyp gene cluster.

Archives of microbiology - 1 Nov 1998

Buhrke T, Friedrich B

Abstract excerpt

The role of HoxX in hydrogenase biosynthesis of Alcaligenes eutrophus H16 was re-examined. The previously characterized hoxX deletion mutant HF344 and a newly constructed second hoxX mutant carrying a smaller in-frame deletion were studied. The second mutant was impaired in the activity of both the soluble and the membrane-bound hydrogenase. The two hydrogenase activities were reduced by approximately 50% due to...

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Identifiers

PMID: 9799290
DOI: 10.1007/s002030050667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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hoxX (hypX) is a functional member of the Alcaligenes eutrophus hyp gene cluster.PMID 9799290Read ↗

hyp gene products in Alcaligenes eutrophus are part of a hydrogenase-maturation system.Semantic proximity Read ↗

Cloning, nucleotide sequence, and heterologous expression of a high-affinity nickel transport gene from Alcaligenes eutrophus.Semantic proximity Read ↗

Temperature tolerance of hydrogenase expression in Alcaligenes eutrophus is conferred by a single amino acid exchange in the transcriptional activator HoxA.Semantic proximity Read ↗

Construction and properties of a triprotein containing the high-affinity nickel transporter of Alcaligenes eutrophus.Semantic proximity Read ↗

Duplication of hyp genes involved in maturation of [NiFe] hydrogenases in Alcaligenes eutrophus H16.Semantic proximity Read ↗

Subforms and in vitro reconstitution of the NAD-reducing hydrogenase of Alcaligenes eutrophus.Semantic proximity Read ↗

Functional and structural role of the cytochrome b subunit of the membrane-bound hydrogenase complex of Alcaligenes eutrophus H16.Semantic proximity Read ↗

Analysis of a pleiotropic gene region involved in formation of catalytically active hydrogenases in Alcaligenes eutrophus H16.Semantic proximity Read ↗

The hydrogenase gene cluster of Rhizobium leguminosarum bv. viciae contains an additional gene (hypX), which encodes a protein with sequence similarity to the N10-formyltetrahydrofolate-dependent enzyme family and is required for nickel-dependent hydrogenase processing and activity.Semantic proximity Read ↗

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Amino acid replacements at the H2-activating site of the NAD-reducing hydrogenase from Alcaligenes eutrophus.Semantic proximity Read ↗

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