Article
HLA class II immunogenetics of IDDM in Yemenite Jews.
Human immunology - 1 Nov 1998
Israel S, Kwon O J, Weintrob N, Sprecher E, Bloch K, Assa S, Brautbar C, Vardi P
Abstract excerpt
The association between HLA-DR and DQ and insulin dependent diabetes mellitus (IDDM) was analyzed in 47 patients and 76 controls of Yemenite Jewish origin. The IDDM susceptibility alleles DRB1*03011, DQA1*0501, DQB1*02 and DRB1*0402, DQA1*0301, DQB1*0302 found in Caucasians had a very strong pred...
Topics
- Alleles
- Diabetes Mellitus, Type 1
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Genotype
- HLA-D Antigens
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DRB1 Chains
- Haplotypes
- Humans
- Israel
- Jews
- Odds Ratio
- Polymerase Chain Reaction
