A Huntington disease-like neurodegenerative disorder maps to chromosome 20p.

doi:10.1086/302093

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Article

A Huntington disease-like neurodegenerative disorder maps to chromosome 20p.

American journal of human genetics - 1 Nov 1998

Xiang F, Almqvist E W, Huq M, Lundin A, Hayden M R, Edström L, Anvret M, Zhang Z

Abstract excerpt

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor disturbance, cognitive loss, and psychiatric manifestations. The disease is associated with a CAG trinucleotide-repeat expansion in the Huntington gene (IT15) on chromosome 4p16.3. One family with a...

Topics

Adult
Age of Onset
Atrophy
Brain
Chromosome Mapping
Chromosomes, Human, Pair 20
Chromosomes, Human, Pair 4
Female
Genetic Markers
Genotype
Humans
Huntington Disease
Magnetic Resonance Imaging
Male
Middle Aged
Neurodegenerative Diseases
Pedigree
Sweden

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Identifiers

PMID: 9792871
DOI: 10.1086/302093
PMCID: PMC1377554

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9792871-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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