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Article

Adverse effects of reverse transcriptase inhibitors

1 Oct 1998

Abstract excerpt

Introduction After zidovudine (ZDV), a 3′-azido analogue of thymidine, was found to be an effective antiretroviral drug against HIV [1,2], other nucleoside analogues inhibiting reverse transcriptase (RT) soon followed: didanosine (ddI), zalcitabine (ddC), lamivudine (3TC), stavudine (D4T), and recently abacavir (1592U89) [3–7]. These drugs have demonstrated efficacy in reduction of morbidity and mortality,...

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PMID: 9792373
DOI: 10.1097/00002030-199814000-00004

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