Article
Increased apolipoprotein E4 allele frequency is associated with vascular dementia in the Hungarian population.
Acta neurologica Scandinavica - 1 Sept 1998
Kálmán J, Juhász A, Császár A, Kanka A, Rimanóczy A, Janka Z, Raskó I
Abstract excerpt
INTRODUCTION: The regulatory role of apolipoprotein E in lipid transport and metabolism was utilized to investigate the allelic association between the apolipoprotein E4 (apoE4) allele and vascular dementia (VD) in a selected sample of Hungarian patients with multiple deep subcortical infarcts and leukoaraiosis. MATERIAL AND METHODS: Thirty-four Caucasian VD cases and 79 healthy control probands were involved in...
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