Article
Prevalence of factor V Leiden mutation in young adults with cerebral ischaemia: a case-control study on 225 patients.
Journal of neurology - 1 Oct 1998
Nabavi D G, Junker R, Wolff E, Lüdemann P, Doherty C, Evers S, Droste D W, Kessler C, Assmann G, Ringelstein E B
Abstract excerpt
Cerebral ischaemia in young adults is a well-recognised disease, and approximately half of the cases remain aetiologically unclear despite extensive investigations. Thrombophilias are known to cause a subset of ischaemic strokes in this population. The factor V Leiden (FVL) mutation, causing resistance to activated protein C, has recently been recognised as the most important genetic thrombophilia in the Western...
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