Article
A genetic study of Factor V Leiden (G1691A) mutation in young ischemic strokes with large vessel disease in a South Indian population.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 Oct 2017
Anadure Ravi, Christopher Rita, Nagaraja Dindagur, Narayanan Coimbatore
Abstract excerpt
Factor V Leiden (FVL) has been, by far, the most investigated gene mutation, with 26 studies to date, on its role in arterial strokes. Overall, a meta-analysis of all these studies taken together showed that carriers of the Factor V Leiden allele were 1.33times more likely to develop arterial strokes when compared to controls. We subjected a highly select subset of young strokes, with large vessel infarcts, to...
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