Article
Detection of point mutations associated with resistance of Helicobacter pylori to clarithromycin by hybridization in liquid phase.
Journal of clinical microbiology - 1 Nov 1998
Pina M, Occhialini A, Monteiro L, Doermann H P, Mégraud F
Abstract excerpt
When the standard procedure for determining antibiotic susceptibility of bacteria is used, the results are delayed, especially for bacteria that grow slowly, such as Helicobacter pylori. Treatment for this bacterium may involve clarithromycin, a compound for which resistance has been associated w...
Topics
- Anti-Bacterial Agents
- Base Sequence
- Clarithromycin
- DNA Primers
- Drug Resistance, Microbial
- Gene Amplification
- Genes, Bacterial
- Genotype
- Helicobacter pylori
- Humans
- Immunoenzyme Techniques
- Nucleic Acid Hybridization
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- RNA, Bacterial
- RNA, Ribosomal, 23S
- Sensitivity and Specificity