Article
Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase.
The Journal of biological chemistry - 23 Oct 1998
Pasqualini E, Caillol N, Panicot L, Mas E, Lloubes R, Lombardo D
Abstract excerpt
Specific transcripts for bile salt-dependent lipase (BSDL), a 100-kDa glycoprotein secreted by the human pancreas, were immunodetected in BxPC-3 and SOJ-6 pancreatic tumoral cell lines. Sequencing of fragments, obtained by mRNA reverse transcription and amplification, confirmed the presence of BSDL transcripts in these cancer cells. The protein was detected in lysates of pancreatic tumoral cells, where it was...
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