Article
Expression of SET, an inhibitor of protein phosphatase 2A, in renal development and Wilms' tumor.
1 Oct 1998
Abstract excerpt
The human gene set was originally identified as a component of the set-can fusion gene produced by a somatic translocation event in a case of acute undifferentiated leukemia. In the developing kidney, set was highly expressed in the zone of nephron morphogenesis. Recently, SET was shown to be a potent and specific inhibitor of protein phosphatase 2A, a family of major serine/threonine phosphatases involved in...
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