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Article

Analysis of WT1 target gene expression in stably transfected cell lines.

Oncogene - 10 Sept 1998

Thäte C, Englert C, Gessler M

Abstract excerpt

The Wilms' tumour suppressor gene WT1 encodes a zinc finger protein that is mutated in a subset of Wilms' tumours. Mutation screening and animal studies revealed essential roles during development and later function of the kidneys and the entire genitourinary system. Sequence similarity suggested a possible role for WT1 as a transcription factor. Indeed, sequence specific DNA binding and transcriptional...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9771972
DOI: 10.1038/sj.onc.1202055

Genes

CSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Analysis of WT1 target gene expression in stably transfected cell lines.PMID 9771972Read ↗

Functional properties of WT1.Semantic proximity Read ↗

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Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation.Semantic proximity Read ↗

Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development.Semantic proximity Read ↗

The role of the Wilms tumour gene (<i>WT1</i>) in normal and malignant haematopoiesisSemantic proximity Read ↗

WT1: what has the last decade told us?Semantic proximity Read ↗

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.Semantic proximity Read ↗

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The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryoSemantic proximity Read ↗

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