Article
Galanin regulates prolactin release and lactotroph proliferation.
Proceedings of the National Academy of Sciences of the United States of America - 13 Oct 1998
Wynick D, Small C J, Bacon A, Holmes F E, Norman M, Ormandy C J, Kilic E, Kerr N C, Ghatei M, Talamantes F, Bloom S R, Pachnis V
Abstract excerpt
The neuropeptide galanin is predominantly expressed by the lactotrophs (the prolactin secreting cell type) in the rodent anterior pituitary and in the median eminence and paraventricular nucleus of the hypothalamus. Prolactin and galanin colocalize in the same secretory granule, the expression of both proteins is extremely sensitive to the estrogen status of the animal. The administration of estradiol-17beta...
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