Article
Requisite mutational load, pathway epistasis and deterministic mutation accumulation in sexual versus asexual populations.
Genetica - 1 Jan 1998
Rice W R
Abstract excerpt
A measure of the equilibrium load of deleterious mutations is developed that explicitly incorporates the level of genome-wide linkage disequilibrium. This measure, called the requisite mutational load, is based on the minimal net reproductive rate of the least mutated class necessary to prevent t...
Topics
- Animals
- Biological Evolution
- Crosses, Genetic
- Female
- Genome
- Male
- Models, Genetic
- Mutation
- Recombination, Genetic
- Reproduction
- Selection, Genetic