Harm avoidance moderates the influence of serotonin transporter gene variants on treatment outcome in bipolar patients.

doi:10.1016/j.jad.2009.02.027

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Article

Harm avoidance moderates the influence of serotonin transporter gene variants on treatment outcome in bipolar patients.

Journal of affective disorders - 1 Dec 2009

Mandelli Laura, Mazza Marianna, Martinotti Giovanni, Di Nicola Marco, Tavian Daniela, Colombo Elisa, Missaglia Sara, De Ronchi Diana, Colombo Roberto, Janiri Luigi, Serretti Alessandro

Abstract excerpt

Response to pharmacological treatments is moderated by both genetic and environmental factors. The contribution of such factors is relatively small and complex interactions are likely to be involved. Serotonin transporter gene (SLC6A4) is a major candidate gene associated to response to antidepre...

Topics

Adult
Antidepressive Agents
Bipolar Disorder
Female
Genetic Variation
Genotype
Harm Reduction
Humans
Male
Middle Aged
Serotonin Plasma Membrane Transport Proteins
Treatment Outcome

Source

Open in PubMed

Identifiers

PMID: 19332357
DOI: 10.1016/j.jad.2009.02.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-19332357-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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