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Article

Harm avoidance moderates the influence of serotonin transporter gene variants on treatment outcome in bipolar patients.

Journal of affective disorders - 1 Dec 2009

Mandelli Laura, Mazza Marianna, Martinotti Giovanni, Di Nicola Marco, Tavian Daniela, Colombo Elisa, Missaglia Sara, De Ronchi Diana, Colombo Roberto, Janiri Luigi, Serretti Alessandro

Abstract excerpt

Response to pharmacological treatments is moderated by both genetic and environmental factors. The contribution of such factors is relatively small and complex interactions are likely to be involved. Serotonin transporter gene (SLC6A4) is a major candidate gene associated to response to antidepressant treatment. Moreover, the 5-HTTLPR polymorphism has been associated with anxiety-related traits such as...

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PMID: 19332357
DOI: 10.1016/j.jad.2009.02.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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