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Article

Coronavirus pseudoparticles formed with recombinant M and E proteins induce alpha interferon synthesis by leukocytes.

Journal of virology - 1 Nov 1998

Baudoux P, Carrat C, Besnardeau L, Charley B, Laude H

Abstract excerpt

Transmissible gastroenteritis virus (TGEV), an enteric coronavirus of swine, is a potent inducer of alpha interferon (IFN-alpha) both in vivo and in vitro. Incubation of peripheral blood mononuclear cells with noninfectious viral material such as inactivated virions or fixed, infected cells leads to early and strong IFN-alpha synthesis. Previous studies have shown that antibodies against the virus membrane...

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Identifiers

PMID: 9765403
DOI: 10.1128/JVI.72.11.8636-8643.1998
PMCID: PMC110275

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