Article
A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites.
The American journal of pathology - 1 May 1990
Picker L J, Michie S A, Rott L S, Butcher E C
Abstract excerpt
It has been proposed that the skin is a functionally unique compartment of the immune system, although little direct evidence supporting this hypothesis has been presented. Here we show that lymphocyte populations at cutaneous sites can be differentiated from otherwise similar populations at noncutaneous sites by their preferential expression of an epitope defined by the MAb HECA-452. This MAb recognizes a...
Topics
- Cell Line
- Epitopes
- Humans
- Lymphocytes
- Phenotype
- Skin
- Skin Neoplasms
- T-Lymphocytes