Article
Prolonged phenotypic, functional, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.
Blood - 15 Oct 1998
Baker M P, Eliopoulos A G, Young L S, Armitage R J, Gregory C D, Gordon J
Abstract excerpt
Group I Burkitt lymphoma (BL) cell lines (L3055, Elijah, Louckes, BL2, and BL29) retaining the original biopsy phenotype were found to undergo prolonged phenotypic, functional, and molecular change on short-term exposure to soluble recombinant CD40L trimer. Sensitivity to, extent of, and duration...
Topics
- Antibodies, Anti-Idiotypic
- B-Lymphocytes
- Burkitt Lymphoma
- CD40 Antigens
- CD40 Ligand
- Cell Adhesion
- Cell Division
- Gene Expression Regulation
- Humans
- Intercellular Adhesion Molecule-1
- Interleukin-4
- Membrane Glycoproteins
- Phenotype
- Proto-Oncogene Proteins c-bcl-2
- Recombinant Fusion Proteins
- Tumor Cells, Cultured
