Article
Association between genetic polymorphisms of glutathione S-transferase P1 and N-acetyltransferase 2 and susceptibility to squamous-cell carcinoma of the esophagus.
International journal of cancer - 23 Oct 1998
Morita S, Yano M, Tsujinaka T, Ogawa A, Taniguchi M, Kaneko K, Shiozaki H, Doki Y, Inoue M, Monden M
Abstract excerpt
We examined the effect of genetic polymorphisms of phase-II enzymes, glutathione S-transferase P1 (GSTP1) and N-acetyltransferase2 (NAT2) on susceptibility to esophageal squamous-cell carcinoma To determine the genotypes of the 2 polymorphisms, PCR-based analysis was performed on samples from 66...
Topics
- Adult
- Aged
- Arylamine N-Acetyltransferase
- Biomarkers, Tumor
- Carcinoma, Squamous Cell
- Disease Susceptibility
- Esophageal Neoplasms
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Glutathione Transferase
- Humans
- Logistic Models